Molecular model of the amino acid tyrosine with experimental electron density in front of an X-ray diffractometer at MIT. The tyrosine is part of the crystal structure of phosphoglycerate mutase from M. tuberculosis. See P. Mueller et al. (2005). Acta Cryst. D61, 309-315. (Figure and photograph by Dr. Peter Mueller. Used with permission.)
This course covers the following topics: X-ray diffraction: symmetry, space groups, geometry of diffraction, structure factors, phase problem, direct methods, Patterson methods, electron density maps, structure refinement, how to grow good crystals, powder methods, limits of X-ray diffraction methods, and structure data bases.
*Some translations represent previous versions of courses.