7.27 Principles of Human Disease

Spring 2006

Gene therapy using an adenovirus vector.

Gene therapy using an adenovirus vector. Image courtesy of the U.S. National Library of Medicine.

Course Highlights

This course features a complete set of readings.

Course Description

This course covers current understanding of, and modern approaches to human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer. Topics include: The Genetics of Simple and Complex Traits; Karyotypic Analysis and Positional Cloning; Genetic Diagnosis; The Roles of Oncogenes and Tumor Suppressors in Tumor Initiation, Progression, and Treatment; The Interaction between Genetics and Environment; Animal Models of Human Disease; Cancer; and Conventional and Gene Therapy Treatment Strategies.
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Prof. David Housman
Prof. Jacqueline Lees

Course Meeting Times

Two sessions / week
1.5 hours / session