The role of the Rad checkpoint complex was inferred from the 3-D structure predicted by comparative modeling at Lawrence Livermore National Laboratory. The Rad complex delays cell division to allow time for DNA repair to take place. (Image courtesy of the U.S. Department of Energy Genomics: GTL Program
This subject describes and illustrates computational approaches to solving problems in systems biology. A series of case-studies will be explored that demonstrate how an effective match between the statement of a biological problem and the selection of an appropriate algorithm or computational technique can lead to fundamental advances. The subject will cover several discrete and numerical algorithms used in simulation, feature extraction, and optimization for molecular, network, and systems models in biology.
Special software is required to use some of the files in this course: .zip, .dat, .m, .qif, and .bmp.